Bupivacaine Hydrochloride 37.5?mg ×?5 Vials Wholesale price comparison

Description Contents hide 1 Product Specifications 2 Mechanism of Action 3 Research Applications & Pharmacology 4 Safety Profile & Handling 4.1 ?? Research?Use Disclaimer Product SpecificationsAttributeDetailsProduct NameBupivacaine Hydrochloride Injection (Bu’anma®)Generic NameBupivacaine HydrochlorideCAS Number38396?39?3 / 73360?54?0 accessdata.fda.gov 9store.usp.org 9shharvest.com 9pubchem.ncbi.nlm.nih.govstore.usp.org 2en.wikipedia.org 2zh.wikipedia.org 2Molecular FormulaC??H??N?O·HCl·H?OMolecular Weight~342.9?DaDosage FormSolution for injection (sterile)Strength37.5?mg per 5?mL vialPack Size5 vials per boxApproval NumberH43021018 (NMPA, China)Product Code86904152004254ManufacturerHunan Zhengqing Pharmaceutical Group Co., Ltd.Barcode6922670003720 (verify regionally)StorageStore at 2–25?°C, protect from lightIntended UseLaboratory research use onlyMechanism of ActionBupivacaine blocks voltage-gated sodium channels in neuronal membranes, preventing depolarization and transmission of pain signals. Onset occurs within 5–10 minutes with a duration lasting 2–8 hours—significantly longer than lidocaine.Research Applications & PharmacologyNerve blocks & regional anesthesia: Peripheral, epidural, spinal, or infiltration anesthesia in rodent and large-animal studies .Analgesic pharmacodynamics: Onset typically within 5–10 minutes, peak at ~15–20 minutes, lasting 3–6 hours or longer .Pharmacokinetics: ~95% protein binding, hepatic metabolism, renal excretion; half-life ~3.1?hr in adults .Safety Profile & HandlingAdverse effects:Cardiovascular toxicity (bradycardia, hypotension, arrest) in overdose or IV administration .CNS effects: dizziness, headache, muscle twitching, risk of seizures .Handling precautions:Use proper PPE and biosafety procedures.Monitor cardiovascular and respiratory status in animal models.Avoid rapid IV injection—aspirate before administration to avoid intravascular delivery.Dispose of used vials as pharmaceutical hazardous waste.?? Research?Use DisclaimerThis product is intended exclusively for laboratory research. It is not approved for clinical, diagnostic, therapeutic, or veterinary use. Misuse may pose significant health risks and compromise research integrity.